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Jumat, 19 Februari 2010

Limfoma by AIDS

Lymphoma is one type of cancer in which cells multiply lymph nodes with no control. Lymphomas are divided into two categories: Hodgkin's lymphoma is a distinctive sign of this disease is the discovery of similar cells called Reed-Steinberg cells, and other types of non-Hodgkin's lymphoma (Non-Hodgkin's lymphoma - NHL). NHL cases developed among people with HIV since 1989 remained until 1995. Research continued to investigate the involvement of viruses in producing this type of cancer. However, clinical studies of lymphoma of the brain tissue from AIDS is still very little.

Genesis

NHL is one that attacks cancer cells, especially in lymph nodes and spleen. Leukemia and lymphoma is a common name / commonly used for cancer that attacks white blood cells. Cancer can change the white blood cells at any stage of development from stem cells form in the bone marrow to become T cells and B cells mature. NHL can occur at any stage of HIV disease. HIV-positive cases who have the NHL continues to increase until the year 1995, when the therapy is highly active antiretroviral began to spread. The increase in the number of people with HIV who had the NHL seems proportional to the magnitude and duration of suppression of their immune system.

Lymphoma Causes

Lymphoma occurs when there is a lymphocyte (lymph cells) had a number of genetic mutations and loss of control of reproduction. Cells continue to multiply these mutate and develop into tumors and then attack the lymph tissue such as lymph nodes or spleen. The greatest danger of lymphoma is spreading to other organs or tissue.

Kaposi's sarcoma (KS) in people with HIV is a double infection of HIV and herpes virus causes Kaposi's sarcoma (Kaposi's sarcoma-associated herpesvirus - KSHV) is a new unknown. What about lymphoma in people with HIV? Recent research confirms the active role of Epstein-Barr virus (EBV) in lymphoma development. One type of NHL Burkitt's lymphoma, associated with EBV proven. Around the world, EBV contributes to about half of all cases of cancer of the throat, and more than 30% of all cases of Hodgkin's disease and 10% of NHL. The hypothesis that the HIV virus to empower others to cause certain cancers seem good for further investigation. Research is needed to explain the role of EBV in lymphomas from AIDS, although the relationship between KSHV and KS and the role of human papilloma virus in anogenital cancer seems more understandable. Research is also needed to determine the relationship between the herpes virus that was discovered with lymphoma. Such research could yield new ways to predict and treat lymphoma.

On the other hand, a small-scale study states that there is a relationship between the levels of certain toxins and pesticides in the body of a person with NHL risk. Because of the small number of participants in this study, the research needed to further strengthening.

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